Amitiza (lubiprostone) is a prescription medication used to treat chronic constipation in adults. It is not recommended for use during pregnancy or breastfeeding, and can cause side effects such as nausea, diarrhoea, dizziness and chest pain. Dulcolax (bisacodyl) is an over-the-counter stimulant laxative that can be used to treat constipation. It is not recommended for long-term use as it may cause electrolyte imbalances and the body may develop a tolerance to it over time. There do not appear to be any specific warnings against taking Amitiza and Dulcolax together, but it is always best to consult a doctor before mixing medications.
Characteristics | Values |
---|---|
Brand name | Amitiza |
Generic name | Lubiprostone |
Drug class | Chloride channel activator, Laxative |
Use | Treat chronic constipation in adults, including opioid-induced constipation and irritable bowel syndrome with constipation (IBS-C) in females |
Dosage | 8 mcg or 24 mcg, taken twice daily with food and water |
Side effects | Nausea, diarrhea, dizziness, fatigue, chest pain, chest tightness, shortness of breath, low blood pressure, swelling of arms or legs, mental/mood changes |
Drug interactions | Anticholinergic drugs, loop diuretics (e.g. furosemide), anti-diarrheal medications (e.g. loperamide), methadone |
Warnings | Not recommended for pregnant or breastfeeding women, patients with severe diarrhea or mechanical gastrointestinal obstruction |
What You'll Learn
Amitiza and Dulcolax together
Amitiza (lubiprostone) is a prescription medication used to treat chronic constipation in adults. It is also used to treat irritable bowel syndrome with constipation (IBS-C) in females aged 18 and above. On the other hand, Dulcolax (bisacodyl) is an over-the-counter stimulant laxative. It is not recommended to take Amitiza and Dulcolax together, as they are both laxatives and could cause severe electrolyte imbalances. Additionally, stimulant laxatives like Dulcolax can lead to the development of tolerance over time.
Amitiza is a chloride channel activator that increases fluid in the intestines, aiding stool passage. It is available as an oral capsule taken with food and water, typically twice a day. Amitiza is not a stool softener, fibre, or traditional laxative, but it produces similar effects. It is important to swallow the capsule whole and not break or chew it.
Dulcolax, on the other hand, is a stimulant laxative that stimulates the muscles in the intestines, aiding stool passage. It is available over the counter and is typically taken once a day.
While both medications can be used to treat constipation, it is important to consult a doctor before taking them concurrently, as there may be potential drug interactions or side effects. Additionally, it is crucial to follow the instructions provided by a healthcare professional when taking any medication.
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Amitiza's effectiveness
Amitiza (generic name lubiprostone) is a prescription medication used to treat chronic constipation in adults. It is effective in treating three types of constipation: chronic idiopathic constipation (CIC), irritable bowel syndrome with constipation (IBS-C) in females, and opioid-induced constipation (OIC) in people taking opioid drugs for long-lasting pain unrelated to cancer.
Amitiza is a chloride channel activator, which increases fluid in the intestines to help pass stools. It is available as an oral capsule, typically taken twice a day with food and water. The dosage depends on the patient's condition and response to treatment, ranging from 8 mcg to 24 mcg per day.
Several clinical studies have demonstrated the effectiveness of Amitiza in treating constipation. In one study, 57% of participants with CIC had a bowel movement within 24 hours of taking Amitiza, compared to 37% in the placebo group. Another study found that 80% of those taking Amitiza had a bowel movement within 48 hours, compared to 61% in the placebo group.
Amitiza has also been shown to improve overall symptoms of IBS-C, such as abdominal pain and discomfort, in two separate clinical trials. Additionally, it has been found to increase bowel movements in people with OIC in three clinical studies.
While Amitiza has proven effective in treating constipation, it may cause side effects such as nausea, diarrhoea, stomach pain, gas, bloating, low blood pressure, and allergic reactions. It is important to consult a doctor or pharmacist if these side effects occur or worsen.
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Amitiza's side effects
Amitiza (lubiprostone) is a prescription medication used to treat chronic idiopathic constipation (CIC), irritable bowel syndrome with constipation (IBS-C) in females, and opioid-induced constipation (OIC) in people taking opioid drugs for long-lasting pain unrelated to cancer. It is not a traditional laxative, but it does have a similar effect, increasing fluid in the intestines to help pass stools.
Amitiza can cause both mild and serious side effects. The more common side effects include:
- Nausea (up to 29%)
- Diarrhea (up to 12%)
- Abdominal pain
- Abdominal distention
- Flatulence
- Vomiting
- Loose stools
- Abdominal discomfort
- Dyspepsia
- Dry mouth
- Headache (up to 11%)
- Dizziness
- Palpitations
- Hot flush
- Edema
- Fatigue
- Chest discomfort/pain
- Peripheral edema
- Dyspnea
- Cough
- Muscle spasms
- Joint swelling
- Myalgia
- Fibromyalgia
- Urinary tract infection
- Increased ALT and AST
- Electrolyte imbalance
- Decreased appetite
- Decreased blood potassium
- Weight gain
- Anxiety
- Depression
- Hypersensitivity/allergic-type reactions
Serious side effects are not common, but they can occur. These include:
- Allergic reaction (swelling in the face or hands, swelling or tingling in the mouth or throat)
- Severe gastrointestinal upset (pain or swelling in the belly)
- Low blood pressure (trouble concentrating)
- Weight loss
- Dizziness or lightheadedness
- Trouble breathing
- Chest tightness
- Chest pain
If you experience any of these serious side effects, call your doctor right away. If your symptoms feel life-threatening, call 911 or go to the nearest emergency room.
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Dulcolax's side effects
Dulcolax (bisacodyl) is a stimulant laxative used to treat constipation. It works by increasing intestinal movement, helping stool to pass. It is available over the counter and is typically taken orally as a tablet. However, it can also be administered rectally as a suppository or suspension.
As with any medication, Dulcolax may cause side effects, and these can vary from person to person. Some people may experience only mild side effects, while others may have a more severe reaction. Here is a list of possible side effects associated with the use of Dulcolax:
- Abdominal discomfort, pain, or cramping
- Nausea
- Diarrhea
- Weakness
- Vomiting
- Irregular heartbeat
- Dizziness
- Fainting
- Decreased urination
- Mental or mood changes, such as confusion
- Allergic reactions, such as a rash, itching, or swelling of the face, tongue, or throat
- Rectal irritation and burning
- Dehydration
- Mild skin reactions
It is important to note that this list may not be exhaustive, and some people may experience other side effects not mentioned here. If you experience any side effects, it is always best to consult your doctor or pharmacist for advice, especially if the side effects are severe or persistent. They can provide guidance on managing or mitigating these side effects and can help determine if Dulcolax is the best treatment option for you.
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Amitiza and alcohol
Amitiza (generic name: lubiprostone) is a prescription medication used to treat chronic constipation, constipation caused by opioid pain medicine, and irritable bowel syndrome in women with constipation as the main symptom. It is important to note that Amitiza is only approved for use in adults and should not be used by anyone younger than 18 years old.
Now, regarding Amitiza and alcohol, there are no known interactions or direct contraindications between the two. However, it is important to be mindful of a few things. Firstly, alcohol can be dehydrating, and dehydration can affect constipation. Therefore, it is recommended to follow any alcohol consumption with plenty of water to counteract dehydration.
Secondly, consuming Amitiza can cause dizziness or lightheadedness as a side effect. Drinking alcohol can also cause these effects, so combining the two may worsen them. If dizziness is a concern for you while taking Amitiza, it may be best to avoid alcohol altogether. If you have difficulty avoiding alcohol and it causes you to feel dizzy or lightheaded, be sure to discuss this with your doctor.
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Frequently asked questions
It is not advisable to take Amitiza and Dulcolax together. Both are laxatives and your doctor will likely suggest one or the other depending on your medical history.
Some common side effects of taking Amitiza include nausea, dizziness, fatigue, chest pain, and diarrhoea.
Amitiza is a highly effective medication for treating severe constipation. It is used to treat chronic constipation, constipation caused by opioids, and other types of constipation.
Amitiza is not recommended for pregnant women. Women are advised to use birth control while taking this medication. It is also not advisable to take Amitiza while breastfeeding as it can pass to the baby and cause severe diarrhoea.