Marc Holland
Janumet is a prescription medicine that contains two prescription diabetes medications: sitagliptin (Januvia) and metformin. It is used in conjunction with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Janumet can cause serious side effects, including lactic acidosis, which can lead to death. Lactic acidosis is a rare but serious condition that can occur when taking metformin, one of the medications in Janumet. It is characterized by a buildup of acid in the blood and requires emergency medical attention. While the exact link between Janumet and strokes is unclear, it is known that metformin, one of the medications in Janumet, can increase the risk of lactic acidosis, a serious condition that can have fatal consequences.
| Characteristics | Values |
|---|---|
| Can Janumet cause a stroke? | Yes, Janumet can cause a stroke. |
| What is Janumet? | Janumet is a prescription medicine that contains 2 prescription diabetes medicines, sitagliptin (JANUVIA®) and metformin. |
| What is it used for? | Janumet is used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. |
| Who should not take Janumet? | People with type 1 diabetes, severe kidney problems, diabetic ketoacidosis, or an allergy to any of the ingredients in Janumet should not take Janumet. |
| What are the side effects of Janumet? | Janumet can cause serious side effects such as lactic acidosis, pancreatitis, kidney problems, low vitamin B12, low blood sugar, allergic reactions, joint pain, and skin reactions. |
| What should I do if I experience side effects? | If you experience any side effects, stop taking Janumet and seek medical help immediately. |
Lactic acidosis
Metformin, one of the medicines in Janumet, can cause lactic acidosis. This is more likely if you have liver or kidney disease, congestive heart failure, have had a stroke, a severe infection, surgery, dehydration, are 65 or older, or drink a lot of alcohol.
The symptoms of lactic acidosis include:
- Feeling cold in your hands or feet
- Feeling dizzy or lightheaded
- Having a slow or irregular heartbeat
- Feeling very weak or tired
- Having unusual muscle pain
- Having trouble breathing
- Feeling sleepy or drowsy
- Having stomach pains, nausea, or vomiting
If you experience any of these symptoms, stop taking Janumet and seek emergency medical help.
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Pancreatitis
If you experience any of these symptoms, you should stop taking Janumet and contact your doctor right away.
In addition to pancreatitis, Janumet may also cause lactic acidosis, a rare but serious condition that can lead to death. Lactic acidosis is characterised by symptoms such as unusual muscle pain, dizziness, trouble breathing, and feeling very weak or tired.
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Hypoglycaemia
Signs and symptoms of hypoglycaemia include:
- Hunger
- Dizziness
- Irritability
- Confusion
- Anxiety
- Shakiness
- Headache
- Sleepiness
- Sweating
- Feeling jittery
- Weakness
- Fast heartbeat
If you experience hypoglycaemia, you can quickly treat it by eating or drinking a fast-acting source of sugar, such as fruit juice, hard candy, crackers, raisins, or non-diet soda. You should also inform your doctor about the reaction.
To prevent hypoglycaemia, it is important to eat meals on a regular schedule and not skip meals. It is also recommended to consult your doctor if you plan to miss a meal, as they can advise you on how to manage your blood sugar levels.
Additionally, hypoglycaemia can be more likely to occur if you drink large amounts of alcohol, engage in unusually heavy exercise, or do not consume enough calories from food. Therefore, it is important to limit alcohol consumption, maintain a balanced diet, and consult your doctor before making any significant changes to your exercise routine.
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Allergic reactions
Janumet is a prescription drug used to treat type 2 diabetes in adults. It is a combination of two oral diabetes medications: metformin and sitagliptin. While Janumet is generally well-tolerated, it can cause a range of side effects, including allergic reactions.
If a serious allergic reaction to Janumet is confirmed by a medical professional, they may advise discontinuing the medication and switching to an alternative treatment for diabetes.
It is worth noting that allergic reactions to Janumet do not appear to be common. While serious allergic reactions are listed as a possible side effect, they were not observed in clinical trials of the drug. However, as Janumet contains metformin and sitagliptin, it is important to be aware of potential allergic reactions, especially if you have known allergies to either of these substances.
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Kidney problems
Janumet can cause kidney problems, sometimes requiring dialysis. Metformin, one of the medicines in Janumet, can cause a decrease in the amount of vitamin B12 in your blood, especially if you have had low vitamin B12 blood levels before. Your doctor may do blood tests to check your vitamin B12 levels.
If you take Janumet and experience kidney problems, your doctor may not prescribe Janumet. Before taking Janumet, tell your doctor if you have kidney problems, such as kidney failure. Kidney problems can increase your risk of lactic acidosis with these drugs.
Signs of kidney problems include a change in the amount of urine. If you experience any signs of kidney problems while taking Janumet, contact your doctor right away.
In addition, it is important to note that Janumet should not be used if you have severe kidney disease or diabetic ketoacidosis.
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Frequently asked questions
Janumet can cause a stroke, but this is rare. It is a prescription medicine that contains two prescription diabetes medications, sitagliptin and metformin, and is used to lower blood sugar in adults with type 2 diabetes.
The most common side effects of Janumet include a stuffy or runny nose, sore throat, gas, upset stomach, indigestion, headache, upper respiratory tract infection, weakness, diarrhea, nausea, and vomiting.
Janumet can cause serious side effects, including lactic acidosis, pancreatitis, kidney problems, low vitamin B12, low blood sugar, serious allergic reactions, joint pain, and skin reactions.
If you experience any side effects from Janumet, you should consult your doctor or healthcare provider immediately. It is important to seek medical advice and follow their instructions.
