Polyethylene glycol (PEG) is a medication used to treat constipation. It is available in powder form and works by increasing the amount of water in the intestine, softening the stool, and increasing pressure to prompt muscle movement in the intestines. PEG is typically taken orally and can be mixed with water, juice, soda, coffee, or tea. While it is generally not absorbed by the body and is eliminated through the gastrointestinal tract within 24 to 48 hours, this timeframe can vary depending on individual factors such as age, metabolism, and overall health.
Characteristics | Values |
---|---|
How long does polyethylene glycol stay in the body? | Generally, PEG is eliminated from the body within 24 to 48 hours after ingestion. However, it can be influenced by factors such as age, metabolism, and overall health. It takes an average of one to three days to start working. |
How does it work? | PEG is a laxative that increases the amount of water the intestine absorbs, softening the stool and making it easier to pass. It also increases pressure, prompting the muscles in the intestines to move the stool. |
Dosage | For adult constipation, 17g of PEG 3350 is mixed in 8 ounces of liquid and taken once daily. |
Side effects | Common side effects include flatulence, nausea, stomach cramps, diarrhoea, swollen abdomen, and rectal bleeding. |
Precautions | PEG should not be used for more than one week without a doctor's advice. It should not be used by people with bowel obstruction, appendicitis, inflamed bowel disease, or perforated bowel. |
What You'll Learn
Polyethylene glycol is a medication used to treat constipation
Polyethylene glycol (PEG) is a medication used to treat constipation. It is part of the laxative class of drugs and is available over the counter without a prescription. It is FDA-approved for the treatment of constipation in patients 17 years of age and older. PEG is preferred over other agents for chronic constipation due to its limited adverse effects and better taste. It is also safer than the PEG electrolyte lavage solution as there is no salt absorption.
PEG works by holding water in the stool, softening it, and increasing the number of bowel movements. It is available as a powder that is mixed with a liquid and taken orally. The recommended dosage for adults is 17 grams of PEG 3350 mixed with 8 ounces of liquid, taken once daily. It may take 2 to 4 days for PEG to produce a bowel movement. It should not be used for more than 2 weeks unless directed by a doctor.
Common side effects of PEG include flatulence, nausea, stomach cramps, diarrhoea, swollen abdomen, and rectal hemorrhage. It is important to note that PEG may cause certain liquid thickeners to not work well, increasing the risk of choking. Patients should consult their doctor or pharmacist before using liquid thickeners with this medication.
PEG is contraindicated in patients with known or suspected bowel obstruction, appendicitis, inflamed bowel disease, perforated bowel, and hypersensitivity to polyethylene glycol or any component of the formulation. Patients with electrolyte imbalances and renal impairment should also take precautionary measures.
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It is also used to cleanse the bowel before a colonoscopy
Polyethylene glycol is used to cleanse the bowel before a colonoscopy. Colonoscopies are used to examine the inside of the colon to check for colon cancer and other abnormalities. Polyethylene glycol is often used as a laxative to empty the colon before the procedure. It is typically taken the evening before and/or the morning of the colonoscopy.
The medication comes in powder form and is mixed with water to be consumed orally. It is important to follow the instructions provided by the doctor or the directions on the prescription label. Patients are advised to drink one 8-ounce glass of the solution every 10 to 15 minutes until their liquid bowel movements are clear. It is recommended to drink each glass of the solution quickly rather than sipping it slowly. Staying close to a toilet is advised, as there will be frequent bowel movements during the treatment.
Polyethylene glycol is generally well-tolerated, but some people may experience stomach pain and bloating while taking the medication. In such cases, it is recommended to drink each glass of the solution slowly or allow more time between drinking glasses. It is important to inform the doctor if these symptoms persist.
The use of polyethylene glycol as a bowel preparation for colonoscopy has been found effective in clinical studies. It has been shown to provide superior colon cleansing, improving the quality and accuracy of the colonoscopy procedure. This is crucial for the early detection and treatment of colon cancer and other bowel diseases.
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It is available without a prescription
Polyethylene glycol 3350 (MiraLAX) is a medication used to treat occasional constipation and is available over the counter without a prescription. It belongs to a class of drugs called laxatives. Polyethylene glycol 3350 was previously only available by prescription, and a generic prescription version is still available today. The over-the-counter version is identical to the prescription version, and the main difference is that the prescription option is more likely to be covered by insurance.
Polyethylene glycol 3350 is a safe and effective treatment for constipation, and many people have used it for extended periods under doctor supervision. It is essential to follow the instructions on the package or provided by your doctor when taking this medication.
While polyethylene glycol 3350 is generally well-tolerated, it is always a good idea to speak with a healthcare professional before starting any new medication, even if it is available over the counter. This is especially important if you have any existing medical conditions or are taking other medications, as there may be potential interactions or contraindications.
Additionally, it is worth noting that while polyethylene glycol 3350 can be a helpful treatment for constipation, it should not be relied upon as a long-term solution. It is crucial to address any underlying causes of constipation and make lifestyle changes, such as increasing fibre intake, staying hydrated, and exercising regularly, to promote regular bowel movements.
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It can be used in cosmetic products
Polyethylene glycol (PEG) is a versatile compound with a wide range of applications, including its use in cosmetic products. In cosmetics, PEGs function as emollients, emulsifiers, and vehicles for delivering other ingredients into the skin. The effects of PEGs on the skin are influenced by factors such as their structure, molecular weight, and the overall health of the skin.
PEGs are commonly used in cosmetic products due to their ability to act as penetration enhancers, especially in topical dermatological preparations. They are hydrophilic, which makes them effective in mixing water-based and oil-based ingredients. The cosmetic industry utilizes PEGs as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners.
PEGs are often identified by a number, such as PEG-6 or PEG-8, which represents the approximate molecular weight of the compound. This number is important because it determines how easily the PEG can penetrate the skin, with lower molecular weights having greater penetration capabilities.
PEGs have a variety of derivatives, including PEGylated oils, which have been deemed safe for use in cosmetics. These PEGylated oils, such as PEG-40 and PEG-60 hydrogenated castor oils, are effective solubilizers and emulsifiers. They are used in a range of cosmetic products, including hair care, skin care, and bath products.
The safety of PEGs in cosmetic products has been a subject of study, and while they are generally considered safe, there are some potential risks associated with their use. PEG compounds may contain impurities such as ethylene oxide, 1,4-dioxane, and heavy metals, which are linked to health concerns including cancer. Additionally, PEGs can cause skin irritation and may trigger allergic reactions in some individuals. Therefore, it is recommended to avoid products containing PEGs if you have sensitive or damaged skin.
Overall, PEGs play a significant role in cosmetic products, enhancing the effectiveness of various ingredients and improving the overall performance of the product. However, it is important to be aware of the potential risks associated with their use and make informed decisions when choosing cosmetic products containing PEGs.
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It is safe for pregnant women to use
Polyethylene glycol is a medication used to treat constipation. It is available over the counter and is also available as a prescription medication. It is generally considered safe for short-term use during pregnancy, and it is often a doctor's first choice for easing constipation in pregnant women. However, there is limited research on the use of polyethylene glycol in pregnant women, and some doctors may suggest alternative medications with more research backing their use during pregnancy, such as bisacodyl (Dulcolax) or senna (Fletcher's Laxative).
Polyethylene glycol is classified as a pregnancy category C medicine in the United States, indicating that the systemic absorption of the drug is minimal and it is, therefore, unlikely to cause severe effects on neonates. The American Academy of Family Physicians considers polyethylene glycol the drug of choice for chronic constipation in pregnant women, despite the lack of extensive research on its use during pregnancy.
In Australia, polyethylene glycol is classified as a pregnancy category B1 drug, indicating that it has been taken by a limited number of pregnant women without an increase in the frequency of malformations or other harmful effects on the fetus. Animal studies have not shown evidence of increased fetal damage.
It is important to note that constipation is common during pregnancy due to the pressure of the growing uterus on the intestines, as well as increased hormone levels and prenatal vitamins containing iron. While polyethylene glycol is generally considered safe for short-term use during pregnancy, it is always recommended to consult with a doctor before taking any medication during pregnancy, especially if the constipation is severe. Doctors can help determine if there are other underlying problems causing the constipation and suggest appropriate treatments.
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Frequently asked questions
Polyethylene glycol (PEG) is generally not absorbed by the body and is eliminated through the gastrointestinal tract within 24 to 48 hours after ingestion. However, this timeframe can vary depending on individual factors such as age, metabolism, and overall health.
Polyethylene glycol is a medication used to treat constipation. It works by increasing the amount of water in the intestine, softening the stool, and increasing pressure to prompt bowel movements.
Common side effects of polyethylene glycol include flatulence, nausea, stomach cramps, diarrhoea, swollen abdomen, and rectal bleeding. It is also important to note that overuse may result in dependence on laxatives and chronic constipation.
Polyethylene glycol is typically recommended for short-term use, up to one week. If you need to take it for longer, consult your healthcare provider, as they may suggest an alternative medication or treatment plan.
Polyethylene glycol is considered safe for pregnant women, but it should only be used when clearly needed. It is recommended to discuss the risks and benefits with your doctor.