Citric acid is a component of a medication used to empty the colon before a colonoscopy. This medication is a combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which form magnesium citrate, an osmotic laxative. The medication works by drawing large amounts of water into the intestines and stimulating the colon, causing watery bowel movements (diarrhea). The use of this medication allows for a clearer view of the inside of the colon during a colonoscopy.
Characteristics | Values |
---|---|
Purpose | To clean the colon before a colonoscopy |
Mechanism | Draws large amounts of water into the intestines and stimulates the colon, causing watery bowel movements (diarrhea) |
Dosage form | Powder in packets or liquid in bottles |
Age suitability | Adults and children aged 9 years and older |
Side effects | Nausea, vomiting, bloating, headache, stomach/abdominal cramps, severe nausea, painful bloating, severe stomach cramps, trouble swallowing, trouble drinking liquids, confusion, severe dizziness, fainting, fast/irregular heartbeat, seizure, severe stomach/abdominal pain, bloody stools, rectal bleeding, rash, itching/swelling, trouble breathing |
Drug interactions | Tetracycline, fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, penicillamine, diuretics, heart or blood pressure medication, medicine to treat kidney problems, depression or mental illness medication, seizure medication, NSAIDs (nonsteroidal anti-inflammatory drugs) |
What You'll Learn
- Citric acid, magnesium oxide, and sodium picosulfate is a combination medicine that causes diarrhoea to clean the colon before a colonoscopy
- The medicine is for use in adults and children aged 9 and above
- It can cause severe dehydration, leading to a serious electrolyte imbalance, seizures, kidney failure, or abnormal heartbeats
- It is contraindicated for those with severe renal impairment, gastrointestinal obstruction, bowel perforation, toxic colitis, gastric retention, or hypersensitivity to ingredients
- It is important to follow instructions for use, including consuming only clear liquids the day before the procedure
Citric acid, magnesium oxide, and sodium picosulfate is a combination medicine that causes diarrhoea to clean the colon before a colonoscopy
Citric acid, magnesium oxide, and sodium picosulfate is a medicine used to empty the colon before a colonoscopy. It is suitable for use by adults and children aged 9 and older. The medication is available as a powder (Prepopik) to be mixed with water, or as a solution (Clenpiq) to be taken by mouth. It is typically taken in two doses, with the first dose administered the night before the colonoscopy and the second dose taken on the morning of the procedure.
Citric acid, magnesium oxide, and sodium picosulfate work by causing watery diarrhoea, which helps to empty the stool from the colon. This allows the doctor to have a clear view of the colon walls during the colonoscopy. It is important to follow the instructions provided by your doctor when taking this medication, including consuming only clear liquids during the preparation period and drinking the required amount of fluids to replace the fluid loss.
This medication may cause side effects such as stomach pain, cramps, or fullness. More serious side effects include vomiting, shakiness, sweating, hunger, moodiness, anxiety, changes in heart rate and blood pressure, and bloody or tarry stool. It is important to inform your doctor if you experience any side effects and to seek emergency medical treatment for serious side effects.
Citric acid, magnesium oxide, and sodium picosulfate should not be taken if you have certain medical conditions, such as a blockage in the stomach or intestine, toxic megacolon, or kidney disease. It is also important to inform your doctor about any other medications you are taking, as interactions may occur.
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The medicine is for use in adults and children aged 9 and above
Citric acid is a medicine used in combination with magnesium oxide and sodium picosulfate to empty the colon before a colonoscopy. It is suitable for use in adults and children aged 9 and above.
The medication comes in two forms: a powder (Prepopik) and an oral solution (Clenpiq). It is usually taken in two doses, with clear instructions from a doctor on when to take them. The first dose is generally taken the night before the colonoscopy, and the second dose is taken on the morning of the procedure. However, both doses can also be taken on the day before the colonoscopy.
It is important to follow dietary restrictions when taking this medication. Solid food and milk should be avoided, and only clear liquids should be consumed. Examples of clear liquids include water, light-coloured fruit juice without pulp, clear broth, coffee or tea without milk, flavoured gelatin, popsicles, and soft drinks. It is crucial to not drink any alcoholic or red/purple liquids.
Citric acid, in combination with magnesium oxide and sodium picosulfate, may cause side effects such as stomach pain, cramps, or fullness. More severe side effects include vomiting, especially if it interferes with fluid intake; shakiness, sweating, hunger, moodiness, or anxiety, particularly in children; changes in heart rate and blood pressure that may occur up to seven days after the procedure; and bloody or black and tarry stools. If any of these side effects occur, it is important to seek medical help.
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It can cause severe dehydration, leading to a serious electrolyte imbalance, seizures, kidney failure, or abnormal heartbeats
Dehydration can have severe consequences for the human body, and in extreme cases, it can even be fatal. When dehydrated, the body loses a significant amount of water, which is essential for proper bodily functions. Dehydration can cause a range of issues, from mild symptoms such as fatigue and dark-coloured urine to more severe complications like kidney damage and failure.
One of the most critical risks of dehydration is the potential for severe electrolyte imbalances. Electrolytes are minerals in the body that have an electric charge and are essential for maintaining proper bodily functions. They help regulate nerve and muscle function, balance blood acidity and pressure, and enable the body to absorb nutrients. Common electrolytes include sodium, potassium, calcium, magnesium, chloride, phosphate, and bicarbonate.
When the body is dehydrated, it loses water and electrolytes, leading to an electrolyte imbalance. This imbalance can have severe consequences for the nervous system and can cause seizures. Seizures are a result of abnormal electrical activity in the brain, and electrolyte imbalances can disrupt the electrical signals in the brain, leading to convulsions, muscle spasms, and loss of consciousness.
Additionally, severe dehydration can cause kidney failure. The kidneys are responsible for filtering waste and excess fluid from the blood to produce urine. When dehydrated, the body may not be able to produce enough urine, leading to a buildup of waste and toxins in the body. This can clog the kidneys and cause permanent damage.
Dehydration can also affect heart function, leading to abnormal heartbeats. The heart relies on a balance of fluids and electrolytes to function properly. When dehydrated, the heart may beat faster to compensate for the fluid loss, leading to palpitations. In severe cases, dehydration can cause a dangerous drop in blood pressure, putting strain on the heart and leading to irregular heart rhythms.
To prevent these severe consequences, it is essential to stay hydrated by consuming enough water and replenishing lost fluids and electrolytes, especially during hot weather, intense exercise, or illness.
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It is contraindicated for those with severe renal impairment, gastrointestinal obstruction, bowel perforation, toxic colitis, gastric retention, or hypersensitivity to ingredients
Citric acid is a naturally occurring compound found in citrus fruits, especially lemons and limes. It is also manufactured synthetically from a type of mould and is often used as an additive in food, cleaning agents, and nutritional supplements. While generally recognised as safe by the FDA, citric acid can cause adverse reactions in some people.
Citric acid is contraindicated for those with severe renal impairment, gastrointestinal obstruction, bowel perforation, toxic colitis, gastric retention, or hypersensitivity to ingredients. This means that it is not recommended for people with these conditions and could be harmful.
Those with severe renal impairment, or kidney disease, should not take citric acid. This is because citric acid is filtered by the kidneys and can build up in the body if the kidneys are not functioning properly. This can lead to a condition called citric acid accumulation, which can cause serious health problems.
Gastrointestinal obstruction, or a blockage in the stomach or intestine, is another condition for which citric acid is contraindicated. This is because citric acid can irritate the digestive tract and cause further obstruction. It can also interfere with the absorption of nutrients, which can be dangerous for people with this condition.
Bowel perforation, or a hole in the bowel, is also a contraindication for citric acid. This is because citric acid can irritate the bowel and make the perforation worse. It can also increase the risk of infection and interfere with healing.
Toxic colitis, or inflammation of the colon, is another condition for which citric acid is contraindicated. This is because citric acid can irritate the colon and make the inflammation worse. It can also interfere with the absorption of nutrients, which can be harmful for people with this condition.
Gastric retention, or difficulty emptying the stomach, is another condition that is contraindicated for citric acid. This is because citric acid can slow down the emptying of the stomach and make the condition worse. It can also cause nausea, vomiting, and abdominal pain in people with gastric retention.
Finally, people with hypersensitivity to ingredients in citric acid products should not take them. This includes people with allergies to sodium picosulfate, magnesium oxide, anhydrous citric acid, or any other ingredients in the product. Allergic reactions can range from mild, such as skin rash and itching, to severe, such as anaphylaxis.
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It is important to follow instructions for use, including consuming only clear liquids the day before the procedure
Consuming only clear liquids the day before a colonoscopy is an important part of the procedure's preparation. This is because the bowels must be empty so that the doctor can see the inside of the colon more clearly.
The day before the procedure, you should not eat any solid foods. Instead, you should only consume clear or see-through liquids. Recommended drinks include sports drinks, clear juices like apple and white grape, clear broth, soda, black coffee or tea, gelatin, and ice pops. It is important to avoid red, blue, or purple liquids, as these can discolor the lining of the colon and make it harder for the doctor to see. Alcohol and milk should also be avoided.
In addition to the clear liquid diet, you will also need to take a laxative the day before the procedure. This will help to clean out your colon. The laxative may be a prescription or over-the-counter medication, and it is important to follow the instructions provided by your doctor. Typically, you will need to drink a large volume of liquid laxative, which can be unpleasant, but there are some tricks to help get it down. These include mixing it with something flavored, keeping it well chilled, drinking it through a straw, and following it with something good-tasting.
Overall, it is important to follow all the instructions provided by your doctor for consuming only clear liquids and taking any prescribed laxatives the day before your colonoscopy. This will ensure that the procedure can be carried out effectively and safely.
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